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Despite anything the FDA comes up with - to me FDA approval means very little - they have approved many things that are killing people - there are solutions for women with low testosterone (levels that are low for THEM which can vary) - compounded bio-identical hormones - testosterone, estrogens and progesterone - the identical molecules to what the body makes on it's own - the thing the body recognizes and uses in the normal manner that don't cause the problems created by things that are changed in order to patent them - like prempro. Forty years of use by knowledgable doctors, positive experiences by women and much evidence points to their greater safety and benefits. Wyeth would like us to believe otherwise since the studies showing the dangers of THEIR products (not bio-identical) have bitten into their profits. Women are being lied to and not provided with all the facts about the choices they have. Once is testosterone that has been compounded to the exact dose they need and that can be easily adjusted up or down unlike patches. Get all the facts - read all the evidence - read what doctors who have used these hormones with their patients for years have to say. The FDA is more concerned with drug company products and not very concerned with the health and quality of life of people - especially not women!